Dr. Nina Markoutsaki

Dr. Nina Markoutsaki, MD, MSc, is a Gastroenterologist in Athens with specialist training in digestive oncology, diagnostic gastroenterology and interventional endoscopy.

She currently serves as Director of the 5th Gastroenterology and Interventional Endoscopy Department at Metropolitan General Hospital in Athens.

Her professional background includes medical education and specialist training in Greece, the United Kingdom and France, with clinical experience at Evangelismos General Hospital, Hammersmith Hospital in London and Hôpital Européen Georges-Pompidou in Paris.

Dr. Markoutsaki’s clinical practice covers a broad range of gastrointestinal conditions, including inflammatory bowel disease, irritable bowel syndrome, gastroesophageal reflux disease, colorectal conditions and liver disorders.

A significant part of her professional activity focuses on diagnostic and therapeutic endoscopy, colorectal cancer prevention and the investigation of digestive diseases.

Her scientific background also includes international publications concerning the genetic characteristics of irritable bowel syndrome and research in digestive oncology.

Profile Overview

Dr. Nina Markoutsaki is a Gastroenterologist and Interventional Endoscopist based in Nea Smyrni, Athens.

She graduated from the Medical School of the National and Kapodistrian University of Athens in 2000.

Her early medical career included clinical training in Internal Medicine and Oncology at Metaxa Cancer Hospital in Piraeus, followed by further oncology training at Hammersmith Hospital in London.

Between 2007 and 2011, she completed her specialist training in Gastroenterology at Evangelismos General Hospital in Athens, obtaining her official medical specialty qualification in September 2011.

She subsequently pursued advanced education in Digestive Oncology at Paris Descartes University and Hôpital Européen Georges-Pompidou in France.

In 2012, she obtained the Diplôme Interuniversitaire (DIU) de Cancérologie Digestive, further developing her knowledge of gastrointestinal malignancies.

Today, her professional activity combines clinical gastroenterology, interventional endoscopy and hospital-based medical practice.

Current Position

Dr. Nina Markoutsaki currently serves as Director of the 5th Gastroenterology and Interventional Endoscopy Department at Metropolitan General Hospital in Athens.

She also maintains a private Gastroenterology and Hepatology Practice and Endoscopy Center in Nea Smyrni.

Her clinical work includes the assessment, diagnosis and management of conditions affecting the esophagus, stomach, small intestine, colon, rectum and liver.

As a Gastroenterologist in Athens, she provides diagnostic evaluation for a wide variety of digestive symptoms and disorders.

Her professional responsibilities encompass both routine gastroenterological assessment and specialized endoscopic procedures.

The selection of diagnostic tests and treatment approaches depends on the patient’s symptoms, medical history, clinical findings and individual healthcare needs.

Education & Specialist Training

Dr. Markoutsaki graduated from the Medical School of the National and Kapodistrian University of Athens in 2000 with a degree classification of Very Good.

Her medical education and specialist training include:

• Medical Degree, National and Kapodistrian University of Athens, 2000
• Rural medical service at the Regional Medical Center of Dimitra, Agia, Larissa, 2000–2001
• Training in Internal Medicine at the 2nd Internal Medicine and Oncology Department of Metaxa Cancer Hospital, Piraeus, 2003–2004
• Scientific Associate at the Oncology Department of Metropolitan Hospital, 2005
• Oncology training at Hammersmith Hospital, London, January 2006 – May 2007
• Specialist training in Gastroenterology at the 2nd Gastroenterology Department of Evangelismos General Hospital, Athens, July 2007 – July 2011
• Medical specialty qualification in Gastroenterology, September 2011
• Postgraduate education in Digestive Oncology at Paris Descartes University, 2011–2012
• Scientific collaboration at the Digestive Oncology Department of Hôpital Européen Georges-Pompidou, Paris, January 2012 – January 2013
• Diplôme Interuniversitaire (DIU) de Cancérologie Digestive, June 2012

Her professional education reflects a sustained interest in gastrointestinal diseases, cancer-related digestive conditions and modern diagnostic approaches.

Advanced Training in Digestive Oncology in Paris

An important part of Dr. Nina Markoutsaki’s medical development concerns her specialized education in Digestive Oncology.

Following completion of her Gastroenterology training in Greece, she continued her postgraduate education at the Faculty of Medicine of Paris Descartes University.

In June 2012, she obtained the Diplôme Interuniversitaire de Cancérologie Digestive, a specialized postgraduate qualification focusing on cancers of the digestive system.

Between January 2012 and January 2013, she served as a Scientific Associate at the Service d’Oncologie Digestive of Hôpital Européen Georges-Pompidou in Paris.

Her training was supported by a one-year scholarship from the Hellenic Society of Gastroenterology.

During this period, she gained further experience in a specialized hospital environment dealing with gastrointestinal malignancies.

Her education in Paris complemented her previous oncology training at Hammersmith Hospital in London and Metaxa Cancer Hospital in Greece.

This international clinical experience represents a distinctive aspect of her professional background.

Clinical Expertise

Dr. Markoutsaki’s clinical practice encompasses the investigation and management of conditions affecting the gastrointestinal tract and associated digestive organs.

Her principal areas of clinical interest and activity include:

• Diagnostic Gastroenterology
• Interventional Endoscopy
• Digestive Oncology
• Colonoscopy and colorectal cancer prevention
• Gastroscopy
• Endoscopic polypectomy
• Irritable Bowel Syndrome (IBS)
• Inflammatory Bowel Disease (IBD)
• Gastroesophageal Reflux Disease (GERD)
• Helicobacter pylori infection
• Celiac disease
• Hepatitis and liver disorders
• Chronic constipation and other bowel disorders
• Hemorrhoidal disease and anal conditions

Diagnosis and treatment planning are based on the individual characteristics of each patient and the clinical findings obtained during specialist assessment.

Diagnostic and Interventional Endoscopy

Diagnostic and interventional endoscopy represents a central component of Dr. Nina Markoutsaki’s medical practice.

Endoscopic techniques allow direct examination of different parts of the gastrointestinal tract using specialized instruments equipped with imaging technology.

Depending on the clinical indication, these procedures may be used to investigate symptoms, identify abnormalities, obtain tissue samples or perform selected therapeutic interventions.

Her endoscopic services include:

• Gastroscopy
• Colonoscopy
• Rectoscopy
• Rectosigmoidoscopy
• Endoscopic polypectomy
• Diagnostic biopsies
• Selected endoscopic treatments of gastrointestinal and anorectal conditions

These procedures form part of a broader approach to gastrointestinal disease assessment and management.

Gastroscopy

Gastroscopy is one of the principal diagnostic examinations performed within modern gastroenterology.

The procedure allows examination of the esophagus, stomach and duodenum using a flexible endoscope.

Gastroscopy may be recommended for the investigation of symptoms and conditions such as:

• Persistent heartburn
• Difficulty swallowing
• Upper abdominal discomfort
• Persistent nausea or vomiting
• Gastroesophageal reflux
• Gastritis and peptic ulcers
• Suspected upper gastrointestinal bleeding
• Unexplained weight loss

During the examination, tissue samples may be collected for histological analysis when clinically indicated.

Dr. Markoutsaki includes gastroscopy among the diagnostic and endoscopic services available at her practice.

Colonoscopy & Colorectal Cancer Prevention

Colonoscopy is an important examination for the investigation of lower gastrointestinal symptoms and the prevention of colorectal cancer.

The procedure allows direct visualization of the colon and rectum and may identify inflammation, polyps and other abnormalities.

Colonoscopy can be recommended for several reasons, including:

• Colorectal cancer screening
• Changes in bowel habits
• Rectal bleeding
• Persistent abdominal symptoms
• Investigation of chronic diarrhea
• Assessment of inflammatory bowel disease
• Follow-up after previous colorectal polyps

An important advantage of colonoscopy is the possibility of identifying and removing certain precancerous polyps during the same procedure.

Dr. Nina Markoutsaki performs colonoscopy as part of her clinical activity in diagnostic and interventional gastroenterology.

The timing and frequency of screening depend on factors such as age, family history, previous findings and individual risk.

Artificial Intelligence in Colonoscopy

Modern endoscopic technology is increasingly incorporating artificial intelligence systems designed to support the detection and assessment of colorectal abnormalities.

At Metropolitan General Hospital, AI-assisted colonoscopy has been introduced to support endoscopic examination and improve the identification of potentially significant lesions.

These systems analyze images during the examination and may assist the endoscopist in detecting polyps or areas requiring closer evaluation.

Dr. Nina Markoutsaki directs the hospital’s 5th Gastroenterology and Interventional Endoscopy Department, where this technology is used.

AI-assisted systems are intended to support the medical specialist rather than replace clinical judgment.

The use of advanced imaging technology forms part of continuing developments in gastrointestinal endoscopy and colorectal cancer prevention.

Endoscopic Polypectomy

Endoscopic polypectomy is a therapeutic procedure used to remove selected polyps from the gastrointestinal tract.

Polyps are tissue growths that may develop in the lining of the colon, stomach or other parts of the digestive system.

Although many polyps are benign, certain types can develop precancerous changes over time.

Their identification and removal therefore represent an important part of colorectal cancer prevention.

Dr. Markoutsaki’s endoscopic practice includes the possibility of polyp removal during appropriately indicated examinations.

The decision to remove a polyp depends on factors such as its size, location, appearance and the patient’s medical circumstances.

Digestive Oncology

Digestive Oncology is an important field within Dr. Markoutsaki’s educational and scientific background.

Her specialist training includes experience at oncology departments in Greece, the United Kingdom and France.

Digestive Oncology focuses on malignant diseases affecting organs of the gastrointestinal system, including:

• Esophageal cancer
• Gastric cancer
• Colorectal cancer
• Pancreatic cancer
• Other gastrointestinal malignancies

The evaluation of suspected gastrointestinal malignancy may involve endoscopy, tissue sampling, laboratory investigations and imaging.

Treatment planning for confirmed cancers requires consideration of the disease type, stage, pathology results and overall patient condition, often involving multidisciplinary medical teams.

Dr. Markoutsaki’s experience in Digestive Oncology complements her clinical work in Gastroenterology, particularly in the diagnostic investigation and endoscopic assessment of gastrointestinal disease.

Inflammatory Bowel Disease

Inflammatory Bowel Disease, commonly known as IBD, includes chronic inflammatory conditions affecting the gastrointestinal tract.

The two principal forms are Crohn’s disease and ulcerative colitis.

These conditions may cause recurring symptoms, including abdominal pain, diarrhea, rectal bleeding, fatigue and changes in bowel habits.

Diagnosis usually requires a combination of clinical assessment, laboratory investigations, endoscopy and, when appropriate, imaging or histological examination.

Dr. Markoutsaki’s gastroenterological practice includes the diagnosis and management of inflammatory bowel conditions.

The appropriate management strategy depends on disease activity, location, severity, previous treatment and the patient’s overall medical history.

Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a particular area of scientific interest for Dr. Nina Markoutsaki.

IBS is a disorder of gut-brain interaction that can cause recurring abdominal pain associated with changes in bowel habits.

Symptoms may include abdominal discomfort, bloating, diarrhea, constipation or a combination of these complaints.

The biological mechanisms underlying IBS are complex and involve interactions between gastrointestinal function, the nervous system and other physiological factors.

Dr. Markoutsaki has participated in scientific studies investigating genetic variations potentially associated with IBS in the Greek population.

Her research contributions include publications examining serotonin-related receptor and transporter genes and other genetic polymorphisms.

These studies form part of her broader scientific interest in understanding the biological characteristics and possible genetic predisposition associated with irritable bowel syndrome.

Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease, or GERD, is another condition included within Dr. Markoutsaki’s gastroenterological practice.

GERD occurs when stomach contents repeatedly flow back into the esophagus, potentially causing symptoms such as heartburn and regurgitation.

Some patients may also experience swallowing difficulties, persistent irritation or other symptoms.

Diagnostic evaluation may involve medical history, clinical assessment and gastroscopy when indicated.

Management depends on symptom severity, associated findings, previous treatment and other individual factors.

Liver Diseases & Hepatitis

Hepatology forms part of the broader medical services offered through Dr. Nina Markoutsaki’s gastroenterological practice.

Her clinical activity includes the diagnosis and management of hepatitis and selected liver conditions.

Liver disorders may be associated with viral infections, metabolic factors, medication-related injury or other medical conditions.

Appropriate evaluation can include:

• Medical history and clinical examination
• Liver function tests
• Viral hepatitis investigations
• Imaging examinations
• Additional laboratory testing when indicated

The diagnostic and management strategy depends on the suspected cause, severity of disease and individual clinical findings.

Celiac Disease & Helicobacter pylori

Celiac disease and Helicobacter pylori infection are also included among the gastrointestinal conditions addressed in Dr. Markoutsaki’s practice.

Celiac disease is an immune-mediated condition triggered by gluten in genetically susceptible individuals.

Its diagnosis may involve blood testing and, in selected cases, gastroscopy with small-intestinal biopsies.

Helicobacter pylori is a bacterium that can infect the stomach and is associated with conditions including chronic gastritis and peptic ulcer disease.

Diagnosis may involve non-invasive tests or testing performed during gastroscopy.

Appropriate investigation and treatment depend on the patient’s medical history, symptoms and diagnostic findings.

Anorectal Conditions & Endoscopic Treatments

Alongside general gastroenterology, Dr. Markoutsaki’s practice includes the assessment of selected anorectal conditions.

These include hemorrhoidal disease, anal fissures and certain lesions affecting the anal canal.

Her practice lists diagnostic rectoscopy and rectosigmoidoscopy, as well as treatment services for selected anorectal conditions.

Endoscopic techniques such as argon plasma coagulation may be used for certain lesions when medically appropriate.

The selection of treatment depends on clinical examination, the type of condition and its severity.

Professional Career

Dr. Nina Markoutsaki’s professional career includes clinical experience in Internal Medicine, Oncology, Gastroenterology and specialized Digestive Oncology.

Key stages of her professional development include:

• 2000: Graduated from the Medical School of the National and Kapodistrian University of Athens.
• 2000–2001: Rural medical service at the Regional Medical Center of Dimitra, Agia, Larissa.
• 2003–2004: Training in Internal Medicine at Metaxa Cancer Hospital, Piraeus.
• 2005: Scientific Associate at the Oncology Department of Metropolitan Hospital.
• 2006–2007: Oncology training at Hammersmith Hospital, London.
• 2007–2011: Specialist training in Gastroenterology at Evangelismos General Hospital, Athens.
• 2011: Obtained her medical specialty qualification in Gastroenterology.
• 2011–2012: Postgraduate education in Digestive Oncology at Paris Descartes University.
• 2012–2013: Scientific Associate at the Digestive Oncology Department of Hôpital Européen Georges-Pompidou, Paris.
• 2012: Obtained the Diplôme Interuniversitaire de Cancérologie Digestive.
• Present: Director of the 5th Gastroenterology and Interventional Endoscopy Department at Metropolitan General Hospital.
• Present: Private Gastroenterology and Hepatology Practice in Nea Smyrni, Athens.

Her professional development reflects the combination of specialist hospital education, international clinical training and continued activity in Gastroenterology and Endoscopy.

Scientific Activity & International Publications

Dr. Nina Markoutsaki has contributed to scientific research published in international medical journals.

Her research interests include the biological and genetic mechanisms associated with irritable bowel syndrome, as well as topics concerning gastrointestinal oncology.

Her scientific publications include:

1. Chemosensitivity in ovarian metastases from gastric cancer: a case series

Clinical Research in Hepatology and Gastroenterology, 2013; 37(3):289–295.

This publication examines chemotherapy sensitivity in ovarian metastases originating from gastric cancer, addressing an important clinical issue in the management of metastatic gastrointestinal malignancies.

2. Double pancreatic and gastric adenocarcinomas: A rare association

Clinical Research in Hepatology and Gastroenterology, published online November 14, 2012.

The publication discusses an uncommon association involving pancreatic and gastric adenocarcinomas.

3. Serotonin Transporter and G Protein Beta 3 Subunit Gene Polymorphisms in Greeks with Irritable Bowel Syndrome

Digestive Diseases and Sciences, 2011; 56(11):3276–3280.

This study investigates genetic polymorphisms potentially associated with irritable bowel syndrome in the Greek population.

4. 5-HT2A Receptor Gene Polymorphisms and Irritable Bowel Syndrome

The Journal of Clinical Gastroenterology, 2011; 45(6):514–517.

The research examines the possible relationship between genetic variations involving the serotonin 5-HT2A receptor and irritable bowel syndrome.

5. Current insights into the pathophysiology of Irritable Bowel Syndrome

Gut Pathogens, 2010; 2(1):3.

This publication reviews current knowledge concerning the biological processes and mechanisms involved in irritable bowel syndrome.

6. Intramedullary Spinal Cord Metastases in Breast Cancer: Report of Four Cases and Review of the Literature

Journal of Neuro-Oncology, 2005; 71(1):67–72.

This publication examines cases of intramedullary spinal cord metastases in patients with breast cancer and reviews the relevant medical literature.

These contributions illustrate a scientific background extending across gastroenterology, gastrointestinal oncology and broader oncological research.

Academic Research

In addition to her published scientific work, Dr. Markoutsaki’s academic research has addressed the genetic predisposition associated with Irritable Bowel Syndrome.

Her official academic profile describes doctoral research on the investigation of genetic susceptibility to IBS within the Greek population.

This research subject is closely connected to her published studies on serotonin-related genetic polymorphisms and gastrointestinal function.

Her scientific activity reflects an interest in the relationship between genetic factors and digestive disorders, alongside the clinical investigation and treatment of gastrointestinal diseases.

Professional Memberships

According to her official professional biography, Dr. Nina Markoutsaki maintains affiliations with several Greek and international medical organizations.

These include:

• Hellenic Society of Gastroenterology
• European Society for Medical Oncology (ESMO)
• European Society of Gastrointestinal Endoscopy (ESGE)
• European Society of Digestive Oncology (ESDO)
• American Society for Gastrointestinal Endoscopy (ASGE)
• Hellenic Society of Digestive Oncology

These professional affiliations complement her clinical experience and international education in Gastroenterology, Endoscopy and Digestive Oncology.

Approach to Modern Gastroenterology

Modern Gastroenterology combines clinical evaluation, diagnostic testing and endoscopic technology to investigate conditions affecting the digestive system.

Dr. Markoutsaki’s professional background spans both general Gastroenterology and specialized training in Digestive Oncology.

The assessment of gastrointestinal symptoms requires consideration of several factors, including:

• Presenting symptoms
• Medical and family history
• Previous gastrointestinal conditions
• Laboratory findings
• Endoscopic findings
• Imaging and histological results
• Existing medical treatments
• Overall clinical condition

Not every digestive symptom requires the same investigation or treatment.

A personalized diagnostic approach helps determine which examinations and management options are appropriate for the individual patient.

International Experience & Multilingual Communication

Dr. Markoutsaki’s international medical career includes extended periods of clinical training in London and Paris.

Her professional background is complemented by qualifications in several European languages.

According to her official biography, she holds language qualifications in:

• English
• French
• German
• Italian

Her international clinical education and multilingual background are particularly relevant in Athens, where medical services may be sought by Greek residents, international professionals and patients from other countries.

Dr. Nina Markoutsaki – Gastroenterologist in Athens

Dr. Nina Markoutsaki maintains her private medical practice in Nea Smyrni, Athens.

Her practice operates as a Gastroenterology and Hepatology Medical Office and Endoscopy Center, providing specialist assessment and diagnostic examinations for a range of gastrointestinal conditions.

Her hospital activity at Metropolitan General complements her private practice, connecting general gastroenterological services with specialist interventional endoscopy.

For patients searching for a Gastroenterologist in Athens, her professional profile includes specialist training at Evangelismos General Hospital, oncology experience at Hammersmith Hospital and postgraduate education at Hôpital Européen Georges-Pompidou in Paris.

Her scientific publications and training in Digestive Oncology also form part of her broader medical background.

Why Choose Dr. Nina Markoutsaki?

Dr. Nina Markoutsaki combines specialist training in Gastroenterology with international clinical experience, scientific research and expertise in Digestive Oncology.

Her professional profile includes:

• Medical Degree from the National and Kapodistrian University of Athens
• Gastroenterology specialist qualification
• Clinical training at Evangelismos General Hospital
• Oncology training at Hammersmith Hospital, London
• Advanced education in Digestive Oncology at Paris Descartes University
• Scientific collaboration at Hôpital Européen Georges-Pompidou
• DIU qualification in Digestive Oncology
• Director of the 5th Gastroenterology and Interventional Endoscopy Department at Metropolitan General
• Clinical experience in diagnostic and interventional endoscopy
• Colonoscopy, gastroscopy and endoscopic polypectomy
• Scientific publications in international medical journals
• Research on genetic polymorphisms associated with Irritable Bowel Syndrome
• Membership in Greek, European and American medical societies
• Multilingual communication skills

Her professional background brings together clinical practice, international specialist education and scientific research across different areas of modern Gastroenterology.